Mouse Monoclonal Antibody to WIF1
货号:
30111
别名:
WIF-1; WIF
应用:
WB,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9Y5W5
规格:
目录价
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Description |
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The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. |
References |
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1. BMC Cancer. 2009 Jul 1;9:217. 2. Cancer Res. 2009 Nov 15;69(22):8603-10. |
Specification |
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Aliases | WIF-1; WIF |
Entrez GeneID | 11197 |
Swissprot | Q9Y5W5 |
clone | 1G5 |
WB Predicted band size | 42kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human WIF1 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
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Western blot analysis using WIF1 mouse mAb against Hela (1), NIH/3T3 (2) and NTERA-2 (3) cell lysate.
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Immunofluorescence analysis of Hela cells using WIF1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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Immunohistochemical analysis of paraffin-embedded human ovary tumour tissues (left) and lung cancer (right) using WIF1 mouse mAb with DAB staining.