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Mouse Monoclonal Antibody to TNFRSF11B
货号: 30125
别名: OPG; TR1; OCIF; MGC29565; TNFRSF11B
应用: IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: O00300
规格:
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Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

References

1. Am J Hypertens. 2009 Nov;22(11):1167-70.
2. Am J Hum Genet. 2009 Nov;85(5):628-42.

Specification

Aliases OPG; TR1; OCIF; MGC29565; TNFRSF11B
Entrez GeneID 4982
Swissprot O00300
clone 5G2
WB Predicted band size 60kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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