Mouse Monoclonal Antibody to TNFRSF11B
货号:
30125
别名:
OPG; TR1; OCIF; MGC29565; TNFRSF11B
应用:
IF,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O00300
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
References |
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1. Am J Hypertens. 2009 Nov;22(11):1167-70. 2. Am J Hum Genet. 2009 Nov;85(5):628-42. |
Specification |
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Aliases | OPG; TR1; OCIF; MGC29565; TNFRSF11B |
Entrez GeneID | 4982 |
Swissprot | O00300 |
clone | 5G2 |
WB Predicted band size | 60kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human TNFRSF11B expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |