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Rabbit Polyclonal Antibody to BMPR2
货号: P07709
别名: BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q13873
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Description

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Specification

Aliases BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II
Swissprot Q13873
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human BMPR2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/25-1/100
ELISA 1/2000-1/5000
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