Rabbit Polyclonal Antibody to BMPR2
货号:
P07709
别名:
BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II
应用:
IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q13873
规格:
目录价
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Description |
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This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. |
Specification |
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Aliases | BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II |
Swissprot | Q13873 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human BMPR2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P07709(BMPR2 Antibody) at dilution 1/35. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07709(BMPR2 Antibody) at dilution 1/35. (Original magnification: ×200)