Mouse Monoclonal Antibody to TAB2
货号：
30123
别名：
CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NYJ8
规格：
目录价
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Description |
|---|
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
References |
|---|
| 1. J Clin Endocrinol Metab. 2006 Mar;91(3):1056-61. 2. Sci STKE. 2006 Oct 17;2006(357):re13. 3. Am J Hum Genet. 2010 Jun 11;86(6):839-49. |
Specification |
|
|---|---|
| Aliases | CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2 |
| Entrez GeneID | 23118 |
| Swissprot | Q9NYJ8 |
| clone | 3B5 |
| WB Predicted band size | 80kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human TAB2 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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