Rabbit Polyclonal Antibody to SETD2
货号:
P07906
别名:
HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP
应用:
IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q9BYW2
规格:
目录价
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Description |
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Specification |
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Aliases | HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP |
Swissprot | Q9BYW2 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human SETD2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/50-1/200 |
ELISA | 1/1000-1/5000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07906(SETD2 Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07906(SETD2 Antibody) at dilution 1/30. (Original magnification: ×200)