Rabbit Polyclonal Antibody to KLF17
货号:
P07946
别名:
ZNF393; Zfp393; RP4-675G8.1
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q5JT82
规格:
目录价
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Description |
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Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
Specification |
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Aliases | ZNF393; Zfp393; RP4-675G8.1 |
Swissprot | Q5JT82 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human KLF17 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07946(KLF17 Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07946(KLF17 Antibody) at dilution 1/30. (Original magnification: ×200)