Rabbit Polyclonal Antibody to ICAM1
货号：
P07991
别名：
BB2; CD54; P3.58
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P05362
规格：
目录价
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Description |
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This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Specification |
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|---|---|
| Aliases | BB2; CD54; P3.58 |
| Swissprot | P05362 |
| WB Predicted band size | 58 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human ICAM1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/5000 |
| IHC | 1/50-1/200 |
| ELISA | 1/2000-1/10000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji cells, huvec cells, Primary antibody: P07991(ICAM1 Antibody) at dilution 1/1150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
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The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P07991(ICAM1 Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07991(ICAM1 Antibody) at dilution 1/50. (Original magnification: ×200)
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