Mouse Monoclonal Antibody to SETDB1
货号：
30132
别名：
ESET; KG1T; KMT1E; KIAA0067; H3-K9-HMTase4; SETDB1
应用：
WB,IF
反应种属：
Human,Mouse,Monkey
抗体类型：
Primary antibody
Swissprot：
Q15047
规格：
目录价
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Description |
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This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described. |
References |
|---|
| 1. Proteomics. 2005 Sep;5(14):3589-99. 2. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5308-13. 3. Mol Cell Biochem. 2007 Nov;305(1-2):35-44. |
Specification |
|
|---|---|
| Aliases | ESET; KG1T; KMT1E; KIAA0067; H3-K9-HMTase4; SETDB1 |
| Entrez GeneID | 9869 |
| Swissprot | Q15047 |
| clone | 5H6A12 |
| WB Predicted band size | 180kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Monkey |
| Immunogen | Purified recombinant fragment of human SETDB1 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis using SETDB1 mouse mAb against MCF-7 (1),T47D (2), HEK293 (3), JURKAT (4), NIH/3T3 (5), F9 (6), RAW246.7 (7) and Cos7 (8) cell lysate.
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Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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