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Rabbit Polyclonal Antibody to CD33
货号: P08132
别名: p67; SIGLEC3; SIGLEC-3
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P20138
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Description

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Specification

Aliases p67; SIGLEC3; SIGLEC-3
Swissprot P20138
WB Predicted band size 40 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human CD33
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/50-1/100
ELISA 1/5000-1/10000
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