Rabbit Polyclonal Antibody to FAM3B
货号:
P08309
别名:
2-21; ORF9; PANDER; PRED44; C21orf11; C21orf76
应用:
IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P58499
规格:
目录价
在线咨询
Description |
---|
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. |
Specification |
|
---|---|
Aliases | 2-21; ORF9; PANDER; PRED44; C21orf11; C21orf76 |
Swissprot | P58499 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human FAM3B |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/50-1/200 |
ELISA | 1/2000-1/5000 |
Product Image
-
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08309(FAM3B Antibody) at dilution 1/30. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08309(FAM3B Antibody) at dilution 1/30. (Original magnification: ×200)