Rabbit Polyclonal Antibody to FLNA
货号:
P08338
别名:
FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P21333
规格:
目录价
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Description |
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The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
Specification |
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Aliases | FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280 |
Swissprot | P21333 |
WB Predicted band size | 281 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human FLNA |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/1000-1/5000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: PC3 cells, NIH/3T3 cells, HUVEB cells, Primary antibody: P08338(FLNA Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08338(FLNA Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P08338(FLNA Antibody) at dilution 1/50. (Original magnification: ×200)