Rabbit Polyclonal Antibody to RNF20
货号：
P08709
别名：
BRE1; BRE1A; hBRE1
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q5VTR2
规格：
目录价
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Description |
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The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. |
Specification |
|
|---|---|
| Aliases | BRE1; BRE1A; hBRE1 |
| Swissprot | Q5VTR2 |
| WB Predicted band size | 114 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human RNF20 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/5000 |
| IHC | 1/20-1/100 |
| ELISA | 1/2000-1/10000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Lovo cells, A172 cells, A375 cells, 231 cells, Jurkat cells, hela cells, Primary antibody: P08709(RNF20 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P08709(RNF20 Antibody) at dilution 1/25. (Original magnification: ×200)
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