Mouse Monoclonal Antibody to BECN1
货号:
30182
别名:
ATG6; VPS30; beclin1; BECN1
应用:
WB,IHC,FCM
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q14457
规格:
目录价
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Description |
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Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 (PubMed 19270693)).(supplied by OMIM) . Tissue specificity: Ubiquitous. |
References |
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1. Autophagy. 2008 Oct 1;4(7):947-8. 2. J Clin Invest. 2008 Jun;118(6):2190-9. |
Specification |
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Aliases | ATG6; VPS30; beclin1; BECN1 |
Entrez GeneID | 8678 |
Swissprot | Q14457 |
clone | 2A4 |
WB Predicted band size | 60kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of human BECN1 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
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Western blot analysis using BECN1 mouse mAb against Hela (1), A431 (2), MCF-7 (3), RAJI (4), Jurkat (5) and SKBR-3 (6) cell lysate.
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Flow cytometric analysis of RAJI cells using BECN1 mouse mAb (green) and negative control (purple).
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Immunohistochemical analysis of paraffin-embedded human breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse mAb with DAB staining.