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Rabbit Polyclonal Antibody to DHCR24
货号: P08748
别名: DCE; SELADIN1; Nbla03646; seladin-1
应用: WB,IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q15392
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Description

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Specification

Aliases DCE; SELADIN1; Nbla03646; seladin-1
Swissprot Q15392
WB Predicted band size 60 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human DHCR24
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/30-1/150
ELISA 1/1000-1/2000
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