Rabbit Polyclonal Antibody to SPRY2
货号:
P08801
别名:
IGAN3; hSPRY2
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
O43597
规格:
目录价
在线咨询
Description |
---|
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. |
Specification |
|
---|---|
Aliases | IGAN3; hSPRY2 |
Swissprot | O43597 |
WB Predicted band size | 35 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human SPRY2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/200-1/400 |
ELISA | 1/5000-1/10000 |
Product Image
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A172, LOVO, A375, HepG2 cell lysates, Primary antibody: P08801(SPRY2 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 40 seconds
-
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P08801(SPRY2 Antibody) at dilution 1/200. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08801(SPRY2 Antibody) at dilution 1/200. (Original magnification: ×200)