Mouse Monoclonal Antibody to CD105
货号：
30221
别名：
ENG; END; ORW; HHT1; ORW1; CD105; FLJ41744
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P17813
规格：
目录价
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Description |
|---|
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. |
References |
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| 1. Int J Cancer. 2009 Feb 1;124(3):664-9. 2. Reprod Sci. 2008 Dec;15(10):1018-26. |
Specification |
|
|---|---|
| Aliases | ENG; END; ORW; HHT1; ORW1; CD105; FLJ41744 |
| Entrez GeneID | 2022 |
| Swissprot | P17813 |
| clone | 3A9 |
| WB Predicted band size | 71kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD105 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
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Immunofluorescence analysis of HepG2 cells using CD105 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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Flow cytometric analysis of HepG2 cells using CD105 mouse mAb (green) and negative control (purple).
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Immunohistochemical analysis of paraffin-embedded human kidney cancer tissues (left) and stomach cancer tissues (right) using CD105 mouse mAb with DAB staining.
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