产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Mouse Monoclonal Antibody to PINCH
货号: 30241
别名: PINCH; PINCH1; PINCH-1; LIMS1
应用: WB,IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P48059
规格:
目录价
在线咨询

Description

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

References

1. J Biol Chem. 2009 Feb 27;284(9):5836-44.
2. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20677-82.

Specification

Aliases PINCH; PINCH1; PINCH-1; LIMS1
Entrez GeneID 3987
Swissprot P48059
clone 5G7
WB Predicted band size 37kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PINCH expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852