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Mouse Monoclonal Antibody to CRKL
货号: 30231
别名: CRKL
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P46109
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Description

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

References

1. Mol Cell Biol. 2009 Jun;29(11):3076-87.
2. Cell. 2009 Jul 23;138(2):389-403.

Specification

Aliases CRKL
Entrez GeneID 1399
Swissprot P46109
clone 5E12
WB Predicted band size 39kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CRKL expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000
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