Rabbit Polyclonal Antibody to CDC23
货号:
P09462
别名:
APC8; CUT23; ANAPC8
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q9UJX2
规格:
目录价
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Description |
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The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
Specification |
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Aliases | APC8; CUT23; ANAPC8 |
Swissprot | Q9UJX2 |
WB Predicted band size | 69 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human CDC23 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T, SKOV3 and Hela cell lysates, Primary antibody: P09462(CDC23 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09462(CDC23 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09462(CDC23 Antibody) at dilution 1/20. (Original magnification: ×200)