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Rabbit Polyclonal Antibody to C5AR1
货号: P09415
别名: C5A; C5AR; C5R1; CD88
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P21730
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Description

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

Specification

Aliases C5A; C5AR; C5R1; CD88
Swissprot P21730
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human C5AR1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/40-1/200
ELISA 1/5000-1/10000
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