Rabbit Polyclonal Antibody to COPS8
货号:
P09544
别名:
COP9; CSN8; SGN8
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q99627
规格:
目录价
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Description |
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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Specification |
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Aliases | COP9; CSN8; SGN8 |
Swissprot | Q99627 |
WB Predicted band size | 23 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human COPS8 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human kidney tissue and Human fetal liver tissue, Hela cell lysates, Primary antibody: P09544(COPS8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09544(COPS8 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09544(COPS8 Antibody) at dilution 1/20. (Original magnification: ×200)