Rabbit Polyclonal Antibody to CYFIP1
货号：
P09574
别名：
SHYC; SRA1; SRA-1; P140SRA-1
应用：
IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q7L576
规格：
目录价
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Description |
|---|
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. |
Specification |
|
|---|---|
| Aliases | SHYC; SRA1; SRA-1; P140SRA-1 |
| Swissprot | Q7L576 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human CYFIP1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/25-1/100 |
| ELISA | 1/500-1/1000 |
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