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Rabbit Polyclonal Antibody to DENND1B
货号: P09619
别名: FAM31B; C1ORF18; C1orf218
应用: WB
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q6P3S1
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Description

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Specification

Aliases FAM31B; C1ORF18; C1orf218
Swissprot Q6P3S1
WB Predicted band size 86 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human DENND1B
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
ELISA 1/5000-1/10000
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