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Mouse Monoclonal Antibody to NQO1
货号: 30292
别名: DTD; QR1; DHQU; DIA4; NMOR1; NMORI
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P15559
规格:
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Description

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References

1. Mol Cancer Ther. 2009 Dec;8(12):3369-78.
2. J Biol Chem. 2009 Nov 27;284(48):33233-41.

Specification

Aliases DTD; QR1; DHQU; DIA4; NMOR1; NMORI
Entrez GeneID 1728
Swissprot P15559
clone 4D12
WB Predicted band size 31kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human NQO1 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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