Rabbit Polyclonal Antibody to PDZD3
货号:
P09757
别名:
IKEPP; PDZK2; NHERF4
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q86UT5
规格:
目录价
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Description |
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Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]). |
Specification |
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Aliases | IKEPP; PDZK2; NHERF4 |
Swissprot | Q86UT5 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human PDZD3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09757(PDZD3 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09757(PDZD3 Antibody) at dilution 1/20. (Original magnification: ×200)