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Rabbit Polyclonal Antibody to PLOD2
货号: P09949
别名: LH2; TLH; BRKS2
应用: IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: O00469
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Description

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specification

Aliases LH2; TLH; BRKS2
Swissprot O00469
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human PLOD2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/150-1/300
ELISA 1/5000-1/10000
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