Mouse Monoclonal Antibody to PPP1CA
货号:
30307
别名:
PP-1A; PPP1A; PP1alpha
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P62136
规格:
目录价
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Description |
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The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
References |
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1. J Biol Chem. 2009 Sep 18;284(38):25576-84. 2. Mol Cell Biol. 2009 Jun;29(12):3355-66. |
Specification |
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Aliases | PP-1A; PPP1A; PP1alpha |
Entrez GeneID | 5499 |
Swissprot | P62136 |
clone | 5E9 |
WB Predicted band size | 38kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human PPP1CA expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |