Rabbit Polyclonal Antibody to RPS27A
货号:
P10012
别名:
UBC; S27A; CEP80; UBA80; HEL112; UBCEP1; UBCEP80
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P62979
规格:
目录价
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Description |
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Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified. |
Specification |
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Aliases | UBC; S27A; CEP80; UBA80; HEL112; UBCEP1; UBCEP80 |
Swissprot | P62979 |
WB Predicted band size | 18 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human RPS27A |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/30-1/150 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HL60 cell, Mouse kidney tissue lysates, Primary antibody: P10012(RPS27A Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P10012(RPS27A Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P10012(RPS27A Antibody) at dilution 1/40. (Original magnification: ×200)