Rabbit Polyclonal Antibody to JPT1
货号：
P10010
别名：
HN1; ARM2; HN1A
应用：
IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q9UK76
规格：
目录价
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Description |
|---|
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). |
Specification |
|
|---|---|
| Aliases | HN1; ARM2; HN1A |
| Swissprot | Q9UK76 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human JPT1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/40-1/200 |
| ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10010(JPT1 Antibody) at dilution 1/35. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P10010(JPT1 Antibody) at dilution 1/35. (Original magnification: ×200)
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