Rabbit Polyclonal Antibody to ACTL6B
货号:
P10155
别名:
ACTL6; BAF53B; arpNalpha
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
O94805
规格:
目录价
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Description |
|---|
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. |
Specification |
|
|---|---|
| Aliases | ACTL6; BAF53B; arpNalpha |
| Swissprot | O94805 |
| WB Predicted band size | 47 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human ACTL6B |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/5000 |
| IHC | 1/50-1/300 |
| ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela and HepG2 cell lysates, Primary antibody: P10155(ACTL6B Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds

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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10155(ACTL6B Antibody) at dilution 1/100. (Original magnification: ×200)

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The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P10155(ACTL6B Antibody) at dilution 1/100. (Original magnification: ×200)




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