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Rabbit Polyclonal Antibody to GABARAPL2
货号: P10230
别名: ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
应用: IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: P60520
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Description

Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Specification

Aliases ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
Swissprot P60520
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human GABARAPL2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/40-1/200
ELISA 1/5000-1/10000
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