Rabbit Polyclonal Antibody to GABARAPL2
货号:
P10230
别名:
ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
应用:
IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P60520
规格:
目录价
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Description |
|---|
Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
Specification |
|
|---|---|
| Aliases | ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16 |
| Swissprot | P60520 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human GABARAPL2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/40-1/200 |
| ELISA | 1/5000-1/10000 |


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