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Rabbit Polyclonal Antibody to PHLDA3
货号: P10237
别名: TIH1
应用: IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q9Y5J5
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Description

p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

Specification

Aliases TIH1
Swissprot Q9Y5J5
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human PHLDA3
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/100-1/300
ELISA 1/5000-1/10000
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