Rabbit Polyclonal Antibody to PHLDA3
货号:
P10237
别名:
TIH1
应用:
IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q9Y5J5
规格:
目录价
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Description |
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p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor. |
Specification |
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Aliases | TIH1 |
Swissprot | Q9Y5J5 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human PHLDA3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/100-1/300 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10237(PHLDA3 Antibody) at dilution 1/110. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10237(PHLDA3 Antibody) at dilution 1/110. (Original magnification: ×200)