Rabbit Polyclonal Antibody to ITM2C
货号:
P10318
别名:
E25; BRI3; E25C; ITM3; BRICD2C
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9NQX7
规格:
目录价
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Description |
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Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity). |
Specification |
|
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Aliases | E25; BRI3; E25C; ITM3; BRICD2C |
Swissprot | Q9NQX7 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human ITM2C |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/100-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P10318(ITM2C Antibody) at dilution 1/120. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P10318(ITM2C Antibody) at dilution 1/120. (Original magnification: ×200)