Rabbit Polyclonal Antibody to SAV1
货号:
P10423
别名:
SAV; WW45; WWP4
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q9H4B6
规格:
目录价
在线咨询
Description |
---|
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. |
Specification |
|
---|---|
Aliases | SAV; WW45; WWP4 |
Swissprot | Q9H4B6 |
WB Predicted band size | 45 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human SAV1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/100-1/300 |
ELISA | 1/5000-1/10000 |
Product Image
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HUVEC, PC-3 cell lysates, Primary antibody: P10423(SAV1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
-
The image is immunohistochemistry of paraffin-embedded Human brain tissue using P10423(SAV1 Antibody) at dilution 1/90. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P10423(SAV1 Antibody) at dilution 1/90. (Original magnification: ×200)