Mouse Monoclonal Antibody to FOS
货号：
30360
别名：
p55; AP-1; C-FOS
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P01100
规格：
目录价
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Description |
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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
References |
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| Mol Cell Biochem. 2010 Apr;337(1-2):53-63. Cancer Invest. 2009 Oct;27(8):816-24. |
Specification |
|
|---|---|
| Aliases | p55; AP-1; C-FOS |
| Entrez GeneID | 2353 |
| Swissprot | P01100 |
| clone | 2G2 |
| WB Predicted band size | 40.7kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human FOS expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using FOS mouse mAb against HeLa (1), and HeLa (2) cell lysate.
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Flow cytometric analysis of HeLa cells using FOS mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using FOS mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using FOS mouse mAb with DAB staining.
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