Rabbit Polyclonal Antibody to NR1H2
货号:
P10534
别名:
NER; UNR; LXRB; LXR-b; NER-I; RIP15
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P55055
规格:
目录价
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Description |
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The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]). |
Specification |
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|---|---|
| Aliases | NER; UNR; LXRB; LXR-b; NER-I; RIP15 |
| Swissprot | P55055 |
| WB Predicted band size | 51 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human NR1H2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/100-1/300 |
| ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Rat liver tissue and Mouse liver tissue lysates, Primary antibody: P10534(NR1H2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10534(NR1H2 Antibody) at dilution 1/120. (Original magnification: ×200)



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