Rabbit Polyclonal Antibody to LRWD1
货号:
P10576
别名:
ORCA; CENP-33
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9UFC0
规格:
目录价
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Description |
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The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. |
Specification |
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Aliases | ORCA; CENP-33 |
Swissprot | Q9UFC0 |
WB Predicted band size | 71 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human LRWD1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/100-1/300 |
ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: PC-3 cell lysate, Primary antibody: P10576(LRWD1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10576(LRWD1 Antibody) at dilution 1/80. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P10576(LRWD1 Antibody) at dilution 1/80. (Original magnification: ×200)