Mouse Monoclonal Antibody to HSP90AA1
货号：
30356
别名：
HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4
应用：
WB,IHC,FCM
反应种属：
Human,Mouse,Monkey
抗体类型：
Primary antibody
Swissprot：
P07900
规格：
目录价
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Description |
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HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]). |
References |
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| Mol Biol Cell. 2010 May 1;21(9):1462-9. Mol Cancer Ther. 2009 Dec;8(12):3296-306. |
Specification |
|
|---|---|
| Aliases | HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4 |
| Entrez GeneID | 3320 |
| Swissprot | P07900 |
| clone | 5G5 |
| WB Predicted band size | 90kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Monkey |
| Immunogen | Purified recombinant fragment of human HSP90AA1 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using HSP90AA1 mouse mAb against NIH3T3 (1), HeLa (2), HCT116(3), HL-60 (4) and C0S7 (5) cell lysate.
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Flow cytometric analysis of HeLa cells using HSP90AA1 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using HSP90AA1 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using HSP90AA1 mouse mAb with DAB staining.
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