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Mouse Monoclonal Antibody to RAP1A
货号: 30354
别名: RAP1; KREV1; KREV-1; SMGP21
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P62834
规格:
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Description

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

References

Mol Biol Cell. 2009 Apr;20(7):1916-25.
J Cell Sci. 2009 Aug 15;122(Pt 16):2996-3004.

Specification

Aliases RAP1; KREV1; KREV-1; SMGP21
Entrez GeneID 5906
Swissprot P62834
clone 5F8
WB Predicted band size 21kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human RAP1A expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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