Rabbit Polyclonal Antibody to CTLA4
货号:
P10781
别名:
CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
应用:
IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P16410
规格:
目录价
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Description |
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This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Specification |
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Aliases | CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3 |
Swissprot | P16410 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human CTLA4 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P10781(CTLA4 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P10781(CTLA4 Antibody) at dilution 1/20. (Original magnification: ×200)