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Rabbit Polyclonal Antibody to CTLA4
货号: P10781
别名: CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P16410
规格:
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Description

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Specification

Aliases CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Swissprot P16410
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human CTLA4
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/20-1/100
ELISA 1/5000-1/10000
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