Rabbit Polyclonal Antibody to FBLN5
货号:
P10851
别名:
EVEC; UP50; ADCL2; ARMD3; DANCE; ARCL1A; FIBL-5; HNARMD
应用:
IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q9UBX5
规格:
目录价
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Description |
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The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). |
Specification |
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Aliases | EVEC; UP50; ADCL2; ARMD3; DANCE; ARCL1A; FIBL-5; HNARMD |
Swissprot | Q9UBX5 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human FBLN5 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10851(FBLN5 Antibody) at dilution 1/20. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10851(FBLN5 Antibody) at dilution 1/20. (Original magnification: ×200)