Rabbit Polyclonal Antibody to CLDN7
货号:
P10902
别名:
CLDN-7, CEPTRL2, CPETRL2, Hs.84359, claudin-1
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
O95471
规格:
目录价
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Description |
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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found. |
Specification |
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Aliases | CLDN-7, CEPTRL2, CPETRL2, Hs.84359, claudin-1 |
Swissprot | O95471 |
WB Predicted band size | 23 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human CLDN7 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/1000-1/3000 |
IHC | 1/50-1/150 |
ELISA | 1/1000-1/10000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Human liver cancer tissue, Primary antibody: P10902(CLDN7 Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P10902(CLDN7 Antibody) at dilution 1/50. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human stomach cancer tissue using P10902(CLDN7 Antibody) at dilution 1/50. (Original magnification: ×200)