Rabbit Polyclonal Antibody to PPP1R13L
货号:
P10962
别名:
RAI, RAI4, IASPP, NKIP1
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q8WUF5
规格:
目录价
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Description |
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RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73. |
Specification |
|
|---|---|
| Aliases | RAI, RAI4, IASPP, NKIP1 |
| Swissprot | Q8WUF5 |
| WB Predicted band size | 89 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human PPP1R13L |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50-1/200 |
| ELISA | 1/2000-1/5000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, hela cells, Primary antibody: P10962(PPP1R13L Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P10962(PPP1R13L Antibody) at dilution 1/30. (Original magnification: ×200)

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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10962(PPP1R13L Antibody) at dilution 1/30. (Original magnification: ×200)




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