Rabbit Polyclonal Antibody to MMP8
货号:
P11031
别名:
HNC, CLG1, MMP-8, PMNL-CL
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P22894
规格:
目录价
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Description |
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
Specification |
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Aliases | HNC, CLG1, MMP-8, PMNL-CL |
Swissprot | P22894 |
WB Predicted band size | 53 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human MMP8 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: P11031(MMP8 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P11031(MMP8 Antibody) at dilution 1/45. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11031(MMP8 Antibody) at dilution 1/45. (Original magnification: ×200)