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Mouse Monoclonal Antibody to KRT13
货号: 30391
别名: K13; CK13
应用: WB,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P13646
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Description

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.

References

1.J Oral Sci. 2009 Sep;51(3):355-65.
2.Mol Cell Endocrinol. 2008 Dec 16;296(1-2):1-9.

Specification

Aliases K13; CK13
Entrez GeneID 3860
Swissprot P13646
clone 3G4
WB Predicted band size 52kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human KRT13 (AA: 143-295) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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