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Rabbit Polyclonal Antibody to BCL6
货号: P11239
别名: BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P41182
规格:
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Description

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specification

Aliases BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
Swissprot P41182
WB Predicted band size 79 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human BCL6
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/10-1/50
ELISA 1/5000-1/10000
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