Rabbit Polyclonal Antibody to MYSM1
货号:
P11270
别名:
2ADUB, 2A-DUB, RP4-592A1.1
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q5VVJ2
规格:
目录价
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Description |
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Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
Specification |
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Aliases | 2ADUB, 2A-DUB, RP4-592A1.1 |
Swissprot | Q5VVJ2 |
WB Predicted band size | 95 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human MYSM1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane: Mouse kidney tissue, Primary antibody: P11270(MYSM1 Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
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The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P11270(MYSM1 Antibody) at dilution 1/60. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P11270(MYSM1 Antibody) at dilution 1/60. (Original magnification: ×200)