Rabbit Polyclonal Antibody to NQO1
货号:
P11292
别名:
DTD, QR1, DHQU, DIA4, NMOR1, NMORI
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P15559
规格:
目录价
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Description |
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Specification |
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Aliases | DTD, QR1, DHQU, DIA4, NMOR1, NMORI |
Swissprot | P15559 |
WB Predicted band size | 31 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human NQO1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/1000-1/5000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: P11292(NQO1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11292(NQO1 Antibody) at dilution 1/25. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11292(NQO1 Antibody) at dilution 1/25. (Original magnification: ×200)