Rabbit Polyclonal Antibody to SLC22A17
货号:
P11347
别名:
BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q8WUG5
规格:
目录价
在线咨询
Description |
---|
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. |
Specification |
|
---|---|
Aliases | BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3 |
Swissprot | Q8WUG5 |
WB Predicted band size | 56 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human SLC22A17 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
-
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human esophagus cancer tissue, Primary antibody: P11347(SLC22A17 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
-
The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P11347(SLC22A17 Antibody) at dilution 1/30. (Original magnification: ×200)
-
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P11347(SLC22A17 Antibody) at dilution 1/30. (Original magnification: ×200)