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Rabbit Polyclonal Antibody to ACE
货号: P11456
别名: DCP; ICH; ACE1; DCP1; CD143; MVCD3
应用: WB,IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: P12821
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Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Specification

Aliases DCP; ICH; ACE1; DCP1; CD143; MVCD3
Swissprot P12821
WB Predicted band size 150 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human ACE
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/200-1/1000
IHC 1/100-1/300
ELISA 1/2000-1/5000
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